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Deficiency leads to hypothyroxinemia and, in severe cases, congenital iodine deficiency syndrome characterized by irreversible cognitive impairment (143, 144)

The resulting pellet was resuspended in pre-warmed BO-IVF medium (IVF Bioscience, Falmouth, UK) to a final concentration of 2 10 8 sperm cell/mL

This finding highlights that while GLP-1RAs represent a promising therapeutic avenue for DDES, further comparative effectiveness research is needed to determine their relative efficacy within the modern antidiabetic armamentarium

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