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Results at 48 weeks showed dose-dependent weight loss: 1 mg dose: -8.7% body weight 4 mg dose: -17.1% body weight 8 mg dose: -22.8% body weight 12 mg dose: -24.2% body weight The 24.2% mean weight loss at the highest dose is the largest ever reported for any anti-obesity medication in a clinical trial
Notably, mammals lower blood phosphate levels by enhancing kidney glycolysis and stimulating the synthesis of Gro3P through the activation of cGPDH 44
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