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After natural log transformation, the OR per unit increment was 1.0010 (95% CI: 0.9973 to 1.0046) for -carotene, 0.9985 (95% CI: 0.9804 to 1.0170) for retinol, 1.0000 (95% CI: 0.9989 to 1.0010) for lycopene per 1 g/dL, and 0.9984 (95% CI: 0.9937 to 1.0032) for ascorbate per 1 mol/L

In light of the available pharmacological and non-pharmacological treatments of emphysema and based on the clinical guidelines, such as those of GOLD, a stepwise flowchart of evidence-based treatment could be tailored to the degree of disease severity, taking into consideration the needs of individualized patients [178]

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