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Adipose Tissue Reduction: Besides skeletal health, these compounds have also been studied for their influence on adipose tissue reduction in preclinical models

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Physiology-Cell Physiology 320, C182C194

Electrophysiological recordings further supported this, revealing that Dihexa caused a 1.6-fold increase and Nle-AngIV caused a 1.7-fold increase in the frequency of AMPA-mediated mEPSCs compared to vehicle-treated neurons, indicating an expansion of functional synapses without altering individual synapse properties such as amplitude, rise, or decay times