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Intriguingly, a Western diet high in PUFAs can induce intestinal inflammation in mice lacking one allele of GPX4 in IECs, which implies that dietary PUFAs may be a trigger of GPX4-restricted mucosal inflammation phenocopying aspects of human CD (143)

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The more your body is exposed to toxins, the higher its sulfur demands, and if you do not consume enough sulfur-containing foods, your bodys cysteine and methionine stores may become depleted