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Concluding remarks Since the 1960 s, carnitine as a dietary supplement has already been marketed as therapeutic in a variety of illnesses involving carnitine deficiency and poor oxidation of fatty acid, implying that pharmacologic or nutritional carnitine supplements may be advantageous in some conditions

Other factors, such as sun exposure, genes, and lifestyle can also contribute to a loss of facial volume and sagging skin

Diabetic NASH patients should be preferentially treated with novel drugs licensed for diabetes treatment such as GLP-1RA and SGLT2 inhibitors

All mice were housed under a 12-h light-dark cycle (light on at 8:00, light off at 20:00 pm) and were allowed free access to food and drinking water