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The safety of this mechanism is part of why GLP-1 based therapies have become so widely studied

Notably, only one patient (1.5%) required a dose reduction of oral semaglutide due to gastrointestinal disorders

Supplements discussed include calcium, fiber (such as psyllium), iron, potassium, probiotics, protein, turmeric/curcumin, vitamin B-12, vitamin D, and low-dose lithium, as well as supplements that can affect blood sugar control, supplements for hair loss, and supplements used for skin wrinkles (such as collagen)

So, GLP-1 receptor agonists significantly reduce blood sugar levels and are an effective treatment for type 2 diabetesparticularly the longer-lasting and recent versions of GLP-1s, semaglutide and tirzepatide