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FAQ What is the standard initial dose of vitamin B12 injection for adults with severe deficiency
Despite these points, for studies where efficacy and precise control are paramount, the benefits often outweigh the logistical hurdles
Deficiency leads to nerve damage (neuropathy), which presents as numbness, tingling, or weakness
Other malabsorption causes include: Atrophic gastritis and reduced gastric acid production (common in older adults) Gastrointestinal surgery, particularly gastrectomy, ileal resection, or bariatric surgery (especially gastric bypass) Inflammatory bowel disease affecting the terminal ileum (Crohn's disease) Coeliac disease and other small bowel disorders Chronic pancreatitis affecting enzyme secretion Helicobacter pylori infection (may contribute to reduced absorption) Medication-related deficiency is increasingly recognised
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