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Researchers in the SURMOUNT-1 body composition substudy found that tirzepatide-treated participants lost 33.9% of their fat mass compared to 8.2% in the placebo group

Patients should be advised to monitor blood glucose levels more carefully when consuming alcohol and to ensure adequate food intake to prevent hypoglycemia

Full Dosing Guide Phase 3 TRIUMPH titration schedules week-by-week for 4, 9, and 12 mg targets Weight loss by dose level Phase 2, TRIUMPH-4, and T2D trial data What to do if you miss a dose How retatrutide dosing compares to tirzepatide and semaglutide Stopping retatrutide and tapering Frequently Asked Questions How many units is 2 mg of retatrutide

This creates a situation where a Medicare patient with both type 2 diabetes and obesity might receive tirzepatide covered as Mounjaro for diabetes, with weight loss as a secondary benefit