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However, as the oxidative stress increases and the balance between GSH and GSSG shifts toward GSSG, more cysteines are lost from the system per hour

Pernicious anaemia - the leading cause of B12 deficiency in the UK - is an autoimmune condition whereby your immune system attacks the cells in your stomach that produce intrinsic factor - a protein that your body uses to absorb vitamin B12

Toxicity is also possible from ingestion of a single large dose of vitamin A (for example, ingesting a bottle of supplements at once)