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The brain, after the pancreas, contains the highest density of GLP-1 receptors helping explain GLP-1s impact on appetite regulation and satiety (see Figure 1)

Additionally, some novel GLP-1s hold promise for improved tolerability, as evidenced by Structure Therapeutics phase 2 data for GSBR-1290, which demonstrated encouraging results in terms of AEs and discontinuation rates

The right levels of dopamine are key Medications such as Ritalin and Adderall act to increase dopamine levels in the brain, which is thought to help correct some of the underlying deficits caused by ADHD

Helps: Abdominal fat loss Increased lean muscle mass Decreased fat around muscles Liver Non-alcoholic fatty liver disease Heart Reduces triglycerides Raises IGF-1 levels Reduces Triglycerides Reduces Visceral Adipose Tissue Reduces Carotid Intima Media Size Improves cognition in people over 60 years of age Promotes deep sleep Bone density Immune function Sexual function Mood Memory Cognition Cardiovascular capacity Endurance Energy Exercise capacity Glucose utilization Recovery Wound healing Heart protection Stops telomere shortening Activates stem cells Neuronal repair Works synergistically with hormone replacement therapy COPD CVD Chronic renal failure Chronic respiratory disease