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Unfortunately, GLP-1 levels can decrease due to aging and lifestyle factors

Behavior Change and Implementation Supports Group-based visits Group medical visits (GMVs) or shared medical appointments are an increasingly established, evidence-based modality to provide effective lifestyle therapy in a comprehensive, easy-to-access medium [205]

Practical Strategies and When to Pause or Adjust Treatment If you experience significant fatigue on GLP-1, evidence-backed strategies include optimizing hydration (fluid losses increase with rapid weight loss), ensuring adequate protein intake (minimum 1.2 g/kg to preserve muscle and energy), and checking biomarkers at 46 weeks to identify correctable deficiencies

However, starting at a full dose too often causes side effects like bloating, nausea, or constipation