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For studies that are solely focused on investigating the effect of any intervention on the APAP hepatotoxicity phase, the inclusion of regeneration phase time points should also be considered to rule out any deleterious effects of that intervention on liver regeneration and overall recovery

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These possible complications include the following: Birth defects, miscarriage, or premature birth if taken during pregnancy Joint or bone pain, abnormal bone growth, and osteoporosis (bone thinning or weakening) Visual issues, including reduced night vision Hearing impairment Rare buildup of pressure inside the head (pseudotumor cerebri), with symptoms like blurred vision and nausea Mental health challenges like mood swings, depression, anxiety, or suicidal thoughts