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From a medical view, the goal of treating IBD is mucosal healing/deep remission, which means the patient feels well and does not show signs of inflammation

By inhibiting NF-kB activation, it could potentially reduce the inflammatory cascade that drives flare severity without compromising the immune response to concurrent infections, a common concern during lupus flares when patients may also be on immunosuppressive medications

This reflects the broader gap in the literature, where very early cognitive decline is often overlooked, with research primarily focusing on interventions for diagnosed neurological conditions

European Respiratory Journal 10 (1), 161166 (1997)