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Cellular Targeting: One of ergothioneine's unique properties is its specific cellular transporter (OCTN1), which allows it to accumulate in areas most needed, such as tissues prone to oxidative stress

however, it requires hepatic transformation to its active metabolite via CYP2D6, resulting in unpredictable pharmacokinetics in patients with liver disease

10.1186/s13287-018-1121-9 Summary Keywords nanomedicine, gynecological cancers, extracellular vesicles, stem cell, tissue engineering, regenerative medicine Citation Aldarmahi AA, Khanday S, Taher ES, Abdeen A, Atia GA, Mohammed DA, Nasr DS, Albarakati RG, Zaghamir DE, Hetta HF, Atwa AM, Abass KS, Elmorsy EM, Alshambky A, El-Sakhawy MA, El-Far A and Attia SS (2025) From biomolecules to breakthroughs: exosomes as next-generation theranostics in female infertility