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Payer behavior also adds complexity, with many insurers continuing to impose restrictions on GLP-1s for obesity, while some are more flexible when the drug is prescribed for related conditions

The antidepressant Wellbutrin has also been long-prized for its off-label ability to make cigarettes taste disgusting, a side effect that resulted in the same chemical (bupropion) being rebranded as Zyban, an FDA-approved smoking cessation aid

Track symptoms and medication use