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In experimental studies, AOD-9604 has been observed to stimulate fat oxidation , increase energy expenditure , and reduce adipose tissue accumulation through activation of beta-adrenergic lipolytic pathways

It may be considered: During periods of high stress or fatigue During recovery from illness or surgery When clinical history suggests deficiency risk As part of a broader, supportive infusion plan All decisions are guided by clinical assessment , not symptom trends

Reduces Fat Cell Size and Promotes Lipolysis Research indicates that NNMT inhibition leads to shrinkage of white adipose tissue and a shift toward fat oxidation , making the body more efficient at burning stored fat for energy

Indications include: Medically refractory disease not responding to optimized biologic therapy Bowel obstruction from fibrostenotic stricture Intra-abdominal abscess not amenable to percutaneous drainage Complex perianal fistula (seton placement, diversion) Enterocutaneous or enterovesical fistula Dysplasia or cancer in Crohns colitis Free perforation (rare) Nutritional Therapy Exclusive enteral nutrition (EEN) effective for induction in pediatric Crohns