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GHR are present in skeletal muscle (52), which combined with Fryburgs intra-arterial GH studies, makes a direct GH effect conceivable

In both in-vitro and in-vivo experiments, methylcobalamin inhibited the proliferation of malignant cancerous cells

10.1371/journal.pone.0128221 PLoS One 29 GholampourF.SakiN

Research indicates that autophagy activation may enhance drug resistance in tumor cells during chemotherapy, as autophagy can clear drug-induced cellular damage, thereby protecting tumor cell survival ( 3.4 Epigenetic modifications In recent years, research has demonstrated that epigenetic modifications play a crucial role in the drug resistance of HGSOC, including changes in DNA methylation, histone modifications, and non-coding RNA expression