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Other associations of systemic conditions present in patients included iron deficiency anemia (1 patient, 5.3%), Addisons disease (1 patient, 5.3%), human immunodeficiency virus infection (HIV, 2 patients, 10.5%), and alopecia universalis (1 patient, 5.3%)

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Disruption of IR impairs differentiation of chondrocytes in vitro We next examined the effect of deletion of IR on chondrogenic differentiation in primary chondrocytes

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