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Evidence shows that the strongest genetic risk factor for late-onset AD is the E4 allele of the cholesterol transporter APOE (APOE4), besides, APOE4 could promote amyloid aggregation and impair clearance from the brain directly binding to A (63)

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Thyroid Hormones and Metabolism The thyroid plays a crucial role in weight loss and metabolism

These medications have these effects: Reducing appetite and increasing feelings of fullness Slowing how quickly food leaves the stomach Improving the bodys response to insulin Together, these effects help people eat less and lose weight over time