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The magic drugs are also starting culture wars over fat-shaming, this time reverse-shaming formerly fat people for taking the easy way out by taking the drug

For individuals who have undergone life-changing surgery, weight regain can be distressing and may reintroduce obesity-related comorbidities such as hypertension, obstructive sleep apnoea, and joint problems

Furthermore, most studies focus on a single target or a specific signaling pathway, with limited exploration of the interactions between different targets and pathways

An important aspect of therapy for women with PCOS is to maintain a healthy body weight (132)