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Theres always a bit of wariness when a new class of drugs comes to market because weve seen several times where promising drugs came to market for weight loss and then theyve had to be pulled back, due to safety concerns
Several studies reported that inhibition/depletion of CPT1 leads to apoptosis and suppression of cancer cell proliferation, chemoresistance, and neo-vascularization 24,25,26,27,28
It has a mild calming effect that can support better sleep quality, which is important because poor sleep worsens hunger, cravings, and metabolic health
A phase II trial focusing on individuals with overweight or obesity, coupled with hypertension or dyslipidemia but without T2D, found that cagrilintide (2.4 mg) alongside diet and exercise, led to a 10% body weight reduction compared to 3% with placebo over 26 weeks [99]
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