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These findings, which align with previous reports that pharmacologic inhibition and germline knockout of JNK protect against APAP toxicity [27, 28, 36, 39,40,41,42], support a model where diploid hepatocytes resist injury through suppression of JNK-mediated cell death

Nrgaard CH, Friedrich S, Hansen CT, et al

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4.3.1 Network-based correlation analysis Top-down network analyses have been used to statistically identify keystone taxa and disentangle microbial co-occurrence patterns in a diverse range of ecosystems, including in the human microbiome (Fisher and Mehta, 2014)