long term side effects of glp-1 medications Long-Term GLP-1s: Risks & Benefits – Forbes Health The Long-Term Side Effects of

The effect of these changes is to alter the function of enzyme proteins involved in DNA repair

For some GLP-1 consumers, rapid weight loss can trigger a temporary shedding phase, clinically known as telogen effluvium, pushing follicles prematurely into their resting stage, often surfacing 2-3 months after the initial weight drop begins. A systematic review published in Cureus found that GLP-1 receptor agonists have been associated with several dermatological side effects, including increased alopecia a side effect that has already been linked to real emotional and identity impact for patients (Alsuwailem et al., 2025)

Major exogenous causative factors are infections, intake of particular substances, and radiation, while endogenous factors are mainly sex and genetic disposition (Figure 1)

Discuss any supplements with your healthcare provider to avoid interactions