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For Nissl staining, the sections were subjected to cresyl violet acetate for 15 min at 2325C, rinsed in PBS, dehydrated, transparentized, and mounted before microscopic analysis

Schematic presentation of ROS-mediated lipid peroxidation chain reaction

Figure 1 Cytochrome P450-Mediated Metabolic Activation APAP metabolic activation is mainly catalyzed by the cytochrome P450 enzyme and the reactive metabolite associated with hepatotoxicity is commonly considered to be NAPQI (Jollow et al., 1973)

there was a 32% reduction in the number of patients inappropriately receiving B-12 (521 to 352) , and the proportion of patients receiving B-12 at the correct frequency rose from 58% to 72%