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doi: 10.3389/fphar.2025.1716898 Received 07 October 2025 Revised 03 December 2025 Accepted 08 December 2025 Published 05 January 2026 Volume 16 - 2025 Edited by Venkata Ramireddy Narala, Yogi Vemana University, India Reviewed by Katarzyna Kaczynska, sakowski Medical Research IPolish Academy of Sciences, Poland Chen Chen, Anhui Medical University, China Updates Copyright 2026 Wang and Qiu

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However, individuals with autoimmune conditions, certain genetic variations in glutathione-S-transferase enzymes, or specific medications should consult a provider before long-term supplementation to ensure safety