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Patients planning pregnancy may benefit from a comprehensive consultation that integrates genetic insights with lifestyle optimization, alternative medication options (such as metformin for diabetes, or behavioral interventions for weight), and a timeline for medication transition

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As this new mig-6L(qz2) allele specifically affects its C-terminal protease and lacunin (PLAC) domain via a typical EMS-induced G/C to A/T transition that replaces the last cysteine within the highly conserved six-cysteine region by a tyrosine (Fig.1a, Supplementary Fig

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