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NF-B was found to be hyperactivated during aging, which impairs the generation of induced pluripotent stem cells, as there is a repression of NF-B during the reprogramming process of stem cells towards a pluripotent state [117]

[313] While we acknowledge that certain seasons could experience peak volumes, we proposed to require hospitals to report all four calendar quarters (one full calendar year) of data beginning with the CY 2028 reporting period/CY 2030 payment determination (90 FR 33766)