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Unclassified (IBS-U) Diagnosis Clinical diagnosis using Rome IV criteria Investigations only to rule out organic disease: CBC, CRP, celiac serology, stool tests Colonoscopy if red flags present Management Lifestyle and Diet Increase fiber (soluble fiber for IBS-C) Low FODMAP diet for symptom relief Regular meals, hydration, avoid trigger foods Exercise and stress management Pharmacological IBS-C: laxatives, lubiprostone, linaclotide IBS-D: loperamide, rifaximin Pain / bloating: antispasmodics (hyoscine, dicyclomine) Psychological support: SSRIs or CBT if anxiety/depression present Patient Education Chronic but benign condition Focus on symptom control and lifestyle measures Abdominal pain relieved by defecation is classic Normal labs and imaging

N Engl J Med 2025;393:10771087

Were seeing those are two areas that are helping us drive a lot of the growth for our brands, he said

As we learn more about vitamins and heart health, vitamin Ds role is getting a lot of attention