are there any downsides to glp 1 GLP-1: The Diabetes Drug Changing How We Think About Weight Loss What are GLP-1s? | Mendinground

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Notably, over the subsequent 6 days, we observed a sustained body-weight-lowering effect after infusion of GLP-1MK-801, but not semaglutide, suggesting that the targeted inhibition of NMDA receptors in GLP-1 receptor-positive neurons might promote sustained changes to the defended level of adiposity

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This dramatically slows degradation, preserving potency for months or even years