402,403 In experimental models of depression, which are mainly based on exposure to unpredictable or social stress, numbers of GFAP-positive astrocytes, as well as GFAP levels in cortex and hippocampus, are significantly reduced
In rat models of autoimmune thyroiditis, ginsenosides have demonstrated efficacy in reducing thyroid autoantibody titers by modulating cytokine expression and promoting a balanced Th1/Th2 ratio (Chen et al
In recent years, there have been many studies focusing on the therapeutic and health benefits of the specific bioactive nutraceuticals of mushrooms such as antitumor, antibacterial, antioxidant, antiallergic, immunomodulating, cardiovascular protector, detoxification, antiviral, antifungal, antiparasitic, immune function enhancement, antioxidant, anti-inflammation, hepatoprotective, hypolipidemic, antithrombotic, antidiabetic, hypotensive, antiproliferative, anti-HIV, hypo-cholesterolemic, anticancer, cytotoxic, and anticoagulant activities (Wasser and Weis, 1999
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