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As may be expected, mean diabetes duration tended to be longer in patients receiving a greater number of background medications, ranging from 7.2 to 10.6 years in patients on metformin monotherapy to 8.4 to 17.3 years in patients receiving more than one background medication

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Understanding Semaglutide: A Pathway to Effective Weight Management Semaglutide is an FDA-approved GLP-1 receptor agonist designed for adults struggling with obesity or conditions related to being overweight

Some protocols recommend waiting longer, up to 2 weeks, particularly for patients transitioning from high tirzepatide doses (12.5 mg or 15 mg) to reduce the overlap of active drug and minimize initial side effects