In contrast to findings with behavioral 20,21,22 and other pharmacological interventions 10,12,13 , the similar mean weight loss achieved with semaglutide 2.4 mg in STEP 5 at weeks 52 and 104 (15.6% and 15.2%, respectively) suggests that, on average, there is minimal weight regain over 104 weeks when once-weekly semaglutide therapy is continued
The rate of weight loss with Semaglutide GLP-1 varies from patient to patient and is influenced by factors such as starting weight, dosage, dietary habits, and overall lifestyle
Testosterone Replacement Therapy for male and semaglutide for weight loss may address distinct health concerns
Clinical trial data from the SUSTAIN and STEP programs indicate that nausea, the most frequently reported side effect, generally improves within 46 weeks for most patients as tolerance develops