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Table of Contents Why Retatrutide Can Affect Your Bowel Habits Common Gastrointestinal Side Effects Explained How Long Digestive Symptoms Typically Last Managing Bowel Changes Whilst Taking Retatrutide When to Seek Medical Advice About Digestive Side Effects Talking to Your GP or Prescriber About Your Symptoms Scientific References Frequently Asked Questions Why Retatrutide Can Affect Your Bowel Habits Retatrutide alters bowel habits primarily through GLP-1 receptor activation, which slows gastric emptying and disrupts normal gut motility, causing diarrhoea or constipation depending on the individual

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For context, the placebo group in the same trial lost only 2.4%, making the drug-attributable weight loss approximately 12.5 percentage points