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November 18, 2024

Gastritis is seldom if ever symptomatic, but usually have important clinical sequelae, principally duodenal and gastric ulceration, gastric adenocarcinoma and primary gastric lymphoma (El-Zimaity, 2007

GIP is another hormone involved in insulin release and glucose regulation, so targeting both pathways could create a stronger effect on satiety and blood sugar management compared to GLP-1 alone

American Academy of Neurology guidelines on treating painful DPN recommend that clinicians evaluate oral, topical and nonpharmacologic therapies for patients with painful diabetic polyneuropathy, and emphasizes switching between drug classes rather than trying multiple agents within the same class if one fails [63]