tirzepatide cardiovascular outcomes trial An Observational Study of of vs Glucagon-Like Peptide-1 Receptor Agonists Lilly begins dosing in cardiovascular

Comparison of gut microbial composition between HFD and GQD-treated HFD mice by 16SrDNA sequencing revealed that the ratio of Firmicutes-to-Bacteroidetes was significantly reduced after drug administration, implying that GQD helped to improve gut flora abundance and restore gut homeostasis

As the pounds melted off, there was soon another reason to celebrate

Quantification of 2HG enantiomers 2HG quantification in SCD erythroblasts was performed as we previously described 24 by liquid chromatographymass spectrometry (LC-MS/MS) after derivatization using N-(p-Toluenesulfonyl)-L-phenylalanyl Chloride (TSPC) on the LC-ESI-MS/MS system

doi:10.1056/NEJMoa1612917 297