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Proposed Mechanisms Preventing GABA receptor downregulation Counteracting compensatory NMDA glutamate receptor sensitization Stabilizing benzodiazepine receptor configuration (preventing shift to inverse agonist state) Upregulating GABAergic neurotransmission through pathways distinct from benzodiazepine action itself This tolerance prevention has profound clinical implications
In this case, the B12 shots have started to heal the damaged neurons myelin sheath, but the neural network in which the healed neuron is in, is in a super sensitive state (with extra receptors), so the patient may feel pain or other unpleasant sensations
It is not a general guideline but has been produced to help doctors make the right decision about treatment during the lock-down period
CARENCE EN VITAMINE B12 5
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