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The study aimed to understand the factors influencing changes in health-related quality of life (HRQoL) among individuals with type 2 diabetes in the SUSTAIN 6 trial and to identify potential mediators of the treatment effect of semaglutide on HRQoL scores

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Gastrointestinal disorders, particularly nausea and vomiting, were the most frequent events and accounted for most discontinuations

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