pcos semaglutide Women with seek relief in weight-loss drugs Gracie McGraw on Ozempic, Mounjaro

GLP-1 medications reduce inflammatory markers like CRP and other cytokines

Another common effect is reduced cravings, especially for highly processed, high-calorie foods

Understanding how these routes differ helps contextualize why subcutaneous injection is the standard for the injectable form and what alternatives exist for people who struggle with injections

Limitations include relatively short treatment periods (6 weeks per arm), potential carryover effects despite washout, modest sample size limiting power for subgroup analyses and exclusion of newer agents (e.g., tapentadol) and long-term safety outcomes, which may restrict applicability to broader clinical practice