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10.1073/pnas.1612047113 69

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Before Your Treatment Your doctor will assess if Botox is the right option for you by: Reviewing your medical history Identify if your migraines are chronic or episodic Checking all the medications you have tried Check your neck and head muscles After Your Treatment These are the basic aftercare you should do: Avoid intense exercise for 24 hours Do not rub the injection sites Stay upright for the next 4 hours Hydrate properly Take pain medicines if needed

These effects help resolve inflammation, reduce keratinocyte hyperproliferation, and induce apoptosis in immune cells such as eosinophils and lymphocytes