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For people with diabetes, the weight loss from semaglutide is often a bit lower, typically around 6-9% of total body weight
By mimicking natural incretin hormones, Tirzepatide regulates blood glucose levels and slows gastric emptying
Moreover, the study looked at associations with actual fracture history: for each 1 SD decrease in BMD (T-score drop), the increase in odds of fracture was similar whether using whole-body BMD or hip/spine BMD
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