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Christensen, J
Slowing the dose escalation schedule, temporarily returning to a lower dose, or holding at the current dose longer than recommended are options that can improve tolerability while still achieving therapeutic benefits
This correlates with the results reported by MacAlister et al., (2020a), where plants at the HS sites (characterized by higher temperatures, higher vapor pressure deficits, and less rainfall) were more stressed than at cooler sites as manifested in significantly reduced biomass production, lower photosynthetic and transpiration rates, and slightly higher anthocyanin concentrations
This level of weight loss can have profound positive effects on overall health, reducing the risk of obesity-related conditions such as diabetes, heart disease, and certain cancers
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