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doi:10.1016/S2213-8587(25)00027-0

Of all the organs, the skin is the one that most clearly (and visibly) shows the signs of aging

Changes in Bioactive Compounds Across Menstrual Cycle Bioactive compounds such as phytoestrogens and polyphenols interact with menstrual cycle physiology primarily as modulators of estrogen signaling, oxidative stress, and inflammation, rather than through clearly demonstrated phase-specific endogenous fluctuations or quantifiable requirements