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Many insurance plans restrict GLP-1 coverage to patients with diabetes or BMI above 35, excluding millions who would benefit clinically

Tirzepatide is a dual GLP-1 and GIP receptor agonistmeaning it activates two separate appetite-regulating pathwaysand demonstrates 2022% weight loss in clinical trials over 72 weeks

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Integrative strategies that complement peptide therapy include gut barrier repair with glutamine, zinc carnosine, and probiotics, mast cell modulation with quercetin, vitamin C, and DAO support, nervous system repair with magnesium threonate, omega-3s, and vagal-tone therapies, and anti-inflammatory nutrition using whole-food diets rich in polyphenols and minerals