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The modulation of ferroptotic cell death presents a promising treatment strategy for psoriasis, as evidenced by the efficacy of specific inhibitors such as ferrostatin-1 and liproxstatin-1 in shielding keratinocytes from inflammatory damage in experimental studies (194)

Moreover, genes related to intracellular structure and function, cellcell interactions, and signal transduction (such as genes that encode proteins associated with lysosomes, phagosomes, cell adhesion molecules, and cytokine receptor interactions) were also upregulated

120 There are three subtypes of IDH: IDH1 is located within the cytosol and peroxisomes, and IDH2/3 are primarily found in mitochondria

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