Stop worrying about what to put in your mouth
Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes L Blonde 1, E J Klein, J Han, B Zhang, S M Mac, T H Poon, K L Taylor, M E Trautmann, D D Kim, D M Kendall Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity List of authors
STEP Clinical Trial Program The landmark STEP (Semaglutide Treatment Effect in People with obesity) clinical trial program represents the most extensive investigation of semaglutide for weight management: STEP 1 (New England Journal of Medicine): Enrolled 1,961 adults with obesity or overweight and demonstrated a mean weight loss of 14.9% from baseline at 68 weeks with semaglutide 2.4 mg compared to 2.4% with placebo
The addition of semaglutide to this already high-risk group showed further b12 decline, but whether this represents a medication effect, dietary changes from additional appetite suppression, or natural progression of post-surgical deficiency remains unclear