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The active ingredient in compounded semaglutide is the same molecule that Novo Nordisk sells as Wegovy (FDA-approved for chronic weight management) and Ozempic (FDA-approved for type 2 diabetes, prescribed off-label for weight loss)

Mechanistic investigations using pathway inhibitors or transgenic models are essential to elucidate the causal link between SGLT2 inhibition and hepatic signaling pathways

Future considerations of CTS include use of linked national registries to understand risk factors, explore possible screening methods, and evaluate diagnosis and treatment with a broader perspective beyond surgery, including psychological well-being