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Extensive experimental and computational studies have shown that the binding of GSH to GSTs decreases the p K a of the GSH thiol group from around 9 to about 6 in the active site through hydrogen bonding and salt bridges and through the positive electrostatic potential of the G-site 41,42

Journal of Clinical Investigation, 92(5), 23682376

Combining with Sermorelin (a GHRH analog that helps restore some natural GH pulse amplitude) creates an elegant anti-aging approach: Sermorelin restores the GH axis, AOD targets the adipose tissue directly

(For those of you wanting to go down this rabbit hole, take a look at what happened to phentermine, known on the streets as phen phen) But according to data and Dr