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To evaluate the performance of the PTM site localization algorithm and establish appropriate site confidence score cutoff values for accurate site localization, we initially tested it on a library of synthetic phosphopeptides with known site localization

40 R337C/H/P and L344P influence the synthesis and transcriptional activity of p53 tetramers and are involved in the occurrence of Li-Fraumeni syndrome and Li-Fraumeni-like syndrome