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DIC 8(4):119 Wilding JPH, Batterham RL, Davies M, Van Gaal LF, Kandler K, Konakli K et al (2022) Weight regain and cardiometabolic effects after withdrawal of semaglutide: the STEP 1 trial extension

Weight reduction with GLP-1 receptor agonists typically occurs gradually over 612 months and varies by specific medication

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Since disease prevalence affects sensitivity, specificity, PPV, and NPV, IGF-1 is not a useful screening test in a patient population with low prevalence of GHD